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for transcription-coupled DNA repair (TCR).  We knocked out Rad26, both alone and in conjunction with Ogg1, deletion of which increases the steady state levels of oxidative DNA damage. Results showed that Rad26 depression neither increases nor decreases mutation frequency (WT: 1.5 x 10-7, rad26Δ: 6.8 x 10-8) indicating that it had little to no effects in adaptive mutagenesis at the transcription level. 3:30 – 3:40 - Break3:40 pm - Adaptive Mutagenesis seen in RNA Polymerase Mutant E1230K Alyssa

not to be present at all proceedings, then both shall be given the opportunity to hear and/or read all information presented during the process. If a student chooses to participate but not attend, arrangements must be made at least 24 hours prior to the Review Meeting time. Complainants of other incidents, including but not limited to: Concern for Self and Others, Property Damage, and Vandalism, may be involved in Review Meetings at the discretion of the Office of Student Rights and

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:10 pm - Investigating the effects of oxidative DNA damage in Saccharomyces cerevisiae on survivability and mutagenesis Olivia Egejuru, Senior Capstone Seminar Reactive oxygen species (ROS) are byproducts of normal cellular metabolism. However, their levels can be increased by external factors such as UV-A light or hydrogen peroxide, causing oxidative stress. These ROS can damage the DNA, and if the damage is left unrepaired, it can lead to permanent mutations that may affect the characteristics

envelope can rupture and repair in primary nuclei. However, in micronuclei (MN), the nuclear envelope cannot repair itself. MN, which result from the recruitment of the nuclear envelope to chromosomal fragments or lagging chromosomes, are associated with increased genomic instability and are common in cancer cells. Ruptured MN can neither replicate their DNA nor repair any damage that has occurred. This can increase the likelihood of both mutations and aneuploidies in daughter cells. The non

Section 1. PROMOTION, RANK, AND TENUREPacific Lutheran University seeks faculty with the highest possible qualifications, and offers them conditions of employment commensurate with their professional achievement and conducive to high-quality performance. The university thrives upon the commitment and energy of a diverse faculty. Its programs depend as well upon the variety of faculty appointments that are made, appropriately tenured and untenured, full-time and part-time, emeritus and honorary

Section 1. RANK AND TENURE The faculty shall through the president recommend to the Board of Regents procedures for the granting of tenure. The faculty shall through the president recommend to the Board of Regents requirements for promotion and rank. Section 2. LEAVES OF ABSENCE The faculty shall through the president recommend to the Board of Regents policies for the granting of sabbatical leaves. The faculty shall through the president recommend to the Board of Regents policies for the