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  • being oxidized to a reactive carbamimidoyl nitroso species. This intermediate has the potential to attach to a drug-polymer conjugate systems as reversibly-bound Diels-Alder dienophiles. In this study, a strategy to synthesize hydroxyguanidines involving substitution reactions of hydroxylamines with thiourea derivatives were investigated. The synthesis of the target hydroxyguanidine included generating thiourea using a substituted diamine as the building block of the thiourea and methylation of the

  • professorship. To act in an intermediate capacity in matters concerning the welfare of the faculty as a whole. Official Copy: Provost Office Retention: 5 years, Transfer to University Archives Other Copies: Any member of the committee Retention: End of academic year. Recycle Faculty Assembly Provides an official record of proceedings of the Faculty Assembly. Official Copy: Provost Office Retention: 6 years after end of academic year, transfer to University Archives Other Copies: Any office or faculty member