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nitrosocarbamimides as potential urea prodrugs Anna Tran, Senior Capstone Seminar The use of long-acting injectable medications is an established strategy for sustained drug delivery. A drug-polymer conjugate involving drug release controlled by the rate of retro-Diels-Alder reactions of dienophile-containing prodrugs attached to a polymer-bound diene is a potential new strategy. Nitrosocarbamimides, formed by the oxidation of hydroxyguanidines, are a promising dienophile class that could undergo retro-Diels

scholarship. All honor societies at Pacific Lutheran University serve to enhance the mission of the university. The faculty determines honors bestowed by the university (Faculty Bylaws, Article III, Section 2.A) and therefore all honor societies are reviewed by the faculty to assure both that the academic standards are appropriate to PLU and that the focus of the honor society is an appropriate fit with the PLU mission. A recommendation for instituting a new honor society is to be approved by the faculty

roll as I explained the new time slot (the show was on Saturdays last semester) and the Valentine’s Day theme of the playlist. When I clicked on the first song and turned off the microphone, I realized I’d forgotten to do my consistent opening line. “…where every week, I play a variety of songs, and a fruit basket has a variety of fruit.” OOPS. After making the first mistake, I was nervous. What if the rest of the show fell apart? What if I forgot other details? I tend to catastrophize anything

technically challenging. To get ready for that, we’ll do some concerts on the east coast in Pennsylvania, New York, and I think West Virginia. Why Sergei Rachmaninoff? I grew up surrounded by this music, since I grew up in Russia. For anyone who plays the piano, this particular name is sort of like a sacred name because he was such a tremendous pianist. He wrote such exciting, challenging, and heart-rending music for this instrument. It’s natural that anyone who plays the piano would be drawn to his music

Chapter 3 Every morning now brought its regular duties—shops were to be visited; some new part of the town to be looked at; and the pump-room to be attended, where they paraded up and down for an hour, looking at everybody and speaking to no one. The wish of a numerous acquaintance in Bath was still uppermost with Mrs. Allen, and she repeated it after every fresh proof, which every morning brought, of her knowing nobody at all. They made their appearance in the Lower Rooms; and here fortune was

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security of agency computer systems, and failure to maintain patient confidentiality in any forum is considered a breach of professional and ethical standards. For students this will be reported to the RAP Committee and may result in dismissal from the School of Nursing. The use of social media and other electronic communication has become commonplace in our everyday lives. Every day new outlets, platforms, and applications are created and individuals are increasingly participating in blogs, social

topical foci) Feel free to contact the Center for Community Engagement and Service to customize your process of identifying community partners. Faculty are invited to attend the bi-annual faculty-community breakfast (February and September) as a way to meet new community leaders, and develop connections for future courses.Critical ReflectionCritical ReflectionCritical reflection is an integral part of a service and learning experience. It requires students to thoughtfully consider, analyze and

report the use of a novel assay and replica plate system for the characterization of Saccharomyces cerevisiae that acquired drug resistance to the arginine analogue canavanine. This new technique allowed us to calculate the early mutation rates of clones in a wild type (WT) strain and a strain deficient in a DNA repair glycosylase (ogg1∆), and late mutation frequencies of clones that potentially acquired drug resistance by the Retromutagenesis pathway. Comparison of the late mutation frequencies